Arabinoxylans, gut microbiota and immunity

Mihiri Mendis; Estelle Leclerc; Senay Simsek

doi:10.1016/j.carbpol.2015.11.068

Arabinoxylans, gut microbiota and immunity

Carbohydr Polym. 2016 Mar 30:139:159-66. doi: 10.1016/j.carbpol.2015.11.068. Epub 2015 Nov 29.

Authors

Mihiri Mendis¹, Estelle Leclerc², Senay Simsek³

Affiliations

¹ North Dakota State University, Department of Plant Sciences, Cereal Science Graduate Program, Fargo, ND, USA.
² North Dakota State University, Department of Pharmaceutical Sciences, College of Health Professions, Fargo, ND, USA.
³ North Dakota State University, Department of Plant Sciences, Cereal Science Graduate Program, Fargo, ND, USA. Electronic address: senay.simsek@ndsu.edu.

PMID: 26794959
DOI: 10.1016/j.carbpol.2015.11.068

Abstract

Arabinoxylan (AX) is a non-starch polysaccharide found in many cereal grains and is considered as a dietary fiber. Despite their general structure, there is structural heterogeneity among AX originating from different botanical sources. Furthermore, the extraction procedure and hydrolysis by xylolytic enzymes can further render differences to theses AX. The aim of this review was to address the effects of AX on the gut bacteria and their immunomodulatory properties. Given the complex structure of AX, we also aimed to discuss how the structural heterogeneity of AX affects its role in bacterial growth and immunomodulation. The existing literature indicates the role of fine structural details of AX on its potential as polysaccharides that can impact the gut associated microbial growth and immune system.

Keywords: Arabinoxylan; Bacterial growth; Fine structure; Immunomodulator.

Publication types

Review

MeSH terms

Animals
Gastrointestinal Microbiome / drug effects*
Humans
Immunologic Factors / pharmacology*
Intestines / drug effects*
Intestines / immunology
Intestines / microbiology
Xylans / pharmacology*

Substances

Immunologic Factors
Xylans
arabinoxylan