Testicular Adrenal Rest Tumors (TARTS) With Unusual Histological Features in Congenital Adrenal Hyperplasia (CAH)

Valeri Marianovsky; Olga Bogdanova; Milen Tsvetkov; Denitsa Serteva; Boris Mladenov

doi:10.1016/j.eucr.2015.04.008

Testicular Adrenal Rest Tumors (TARTS) With Unusual Histological Features in Congenital Adrenal Hyperplasia (CAH)

Urol Case Rep. 2015 May 27;3(4):126-8. doi: 10.1016/j.eucr.2015.04.008. eCollection 2015 Jul.

Authors

Valeri Marianovsky¹, Olga Bogdanova², Milen Tsvetkov¹, Denitsa Serteva², Boris Mladenov¹

Affiliations

¹ Department of General and Urgent Urology, University General Hospital for Emergency Medicine "N.I. Pirogov", General Eduard Totleben 21 Blvd, 1606 Sofia, Bulgaria.
² Department of General and Clinical Pathology, University General Hospital for Emergency Medicine "N.I. Pirogov", General Eduard Totleben 21 Blvd, 1606 Sofia, Bulgaria.

Abstract

Congenital adrenal hyperplasia (CAH) patients with testicular adrenal rest tumors (TARTs) with testicular enlargement present a serious diagnostic challenge. According to the data TARTs are usually benign. They are rare, resulting in paucity in the medical literature regarding their pathological features. We report a case of bilateral synchronous mass-forming TARTs with marked cytological and nuclear atypia misinterpreted as malignant testicular tumors in a 40-years-old man with CAH and CT and MRI data for pheochromocytoma of the right adrenal gland and paraaortal and paracaval lymphadenomegaly. He was previously diagnosed with adrenal cortical carcinoma of the left adrenal gland.

Keywords: CAH; Testicular adrenal rest tumors; Testicular mass.

Publication types

Case Reports