Gold(i) operational in synergistic catalysis for the intermolecular α-addition reaction of aldehydes across allenamides

Alberto Ballesteros; Pablo Morán-Poladura; Jose M González

doi:10.1039/c5cc09529h

Gold(i) operational in synergistic catalysis for the intermolecular α-addition reaction of aldehydes across allenamides

Chem Commun (Camb). 2016 Feb 18;52(14):2905-8. doi: 10.1039/c5cc09529h.

Authors

Alberto Ballesteros¹, Pablo Morán-Poladura¹, Jose M González¹

Affiliation

¹ Departamento de Química Orgánica e Inorgánica, Instituto Universitario de Química Organometálica "Enrique Moles", Universidad de Oviedo. C/ Julián Clavería 8, 33006 Oviedo, Spain. jmgd@uniovi.es.

PMID: 26780935
DOI: 10.1039/c5cc09529h

Abstract

The intermolecular reaction of allenamides with aldehydes is reported. The designed approach relies on gold(i) and organocatalysis for activating the allenamides and the aldehydes respectively. Conditions to achieve an enantioselective version of this intermolecular reaction are defined.

Publication types

Research Support, Non-U.S. Gov't