[Omentin: Role in insulin resistance, inflammation and cardiovascular protection]

Arch Cardiol Mex. 2016 Jul-Sep;86(3):233-43. doi: 10.1016/j.acmx.2015.09.010. Epub 2015 Nov 19.
[Article in Spanish]

Abstract

The omentin is an adipokine, which role is due to the capacity of regulate metabolic (insulin sensitivity) and anti-inflammatory activities, thus conferring vascular protection during obesity and diabetes mellitus type 2. By this, it is important to know the mechanisms by which omentin confers cardiovascular protection, with the purpose of establish omentin a possible therapeutic target or molecule on this scenario.

Keywords: Disfunción endotelial; Endotelio; Endothelial dysfunction; Endothelium; Inflamación; Inflammation; Insulin resistance; Mexico; México; Omentin; Omentina; Resistencia a la insulina.

Publication types

  • Review

MeSH terms

  • Cardiovascular Diseases / etiology*
  • Cytokines / physiology*
  • Endothelium, Vascular / physiopathology
  • Energy Metabolism
  • GPI-Linked Proteins / physiology
  • Humans
  • Inflammation / etiology*
  • Insulin Resistance / physiology*
  • Lectins / physiology*
  • Obesity / etiology

Substances

  • Cytokines
  • GPI-Linked Proteins
  • ITLN1 protein, human
  • Lectins