Alkenes with antioxidative activities from Murraya koenigii (L.) Spreng

Bioorg Med Chem Lett. 2016 Feb 1;26(3):799-803. doi: 10.1016/j.bmcl.2015.12.091. Epub 2015 Dec 28.

Abstract

Four new alkenes (1-4), and six known alkenes (5-12) were isolated from Murraya koenigii (L.) Spreng. Their structures were elucidated on the basis of spectroscopic analyses and references. Compounds (1-12) were evaluated for antioxidative activities. Among them, compounds 1, 2, 4, and 7 exhibited significant antioxidative activities using 2,2-diphenyl-1-picrylhydrazyl (DPPH) assay with IC50=21.4-49.5 μM. The known compounds (5-12) were isolated from this plant for the first time.

Keywords: Alkene; Antioxidative activity; Murraya koenigii.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Alkenes / chemistry*
  • Alkenes / isolation & purification
  • Antioxidants / chemistry*
  • Antioxidants / isolation & purification
  • Circular Dichroism
  • Inhibitory Concentration 50
  • Magnetic Resonance Spectroscopy
  • Molecular Conformation
  • Murraya / chemistry*
  • Murraya / metabolism
  • Plant Extracts / chemistry*
  • Plant Leaves / chemistry
  • Plant Leaves / metabolism

Substances

  • Alkenes
  • Antioxidants
  • Plant Extracts