[Salivary gland-type lung tumor: An update]

Ann Pathol. 2016 Jan;36(1):55-62. doi: 10.1016/j.annpat.2015.11.003. Epub 2016 Jan 7.
[Article in French]

Abstract

"Salivary gland-type" tumors arising from the bronchi and lung are rare but not exceptional entities. They are mostly represented by malignant entities such as cystic adenoid carcinoma, mucoepidermoid carcinoma and epithelial/myoepithelial carcinoma. Benign tumors are rare, mainly encompassing pleomorphic adenomas, which are to differentiate from mucous gland adenomas, another entity arising specifically from the peri-bronchial glands. These tumours develop in the proximal bronchi and are not associated with smoke abuse. Their main treatment is surgery. It is important to differentiate them from other broncho-pulmonary tumours as they do not share the same prognosis and therapeutic. This article will review the WHO 2015 classification of these tumours as well as recent updates from the literature to help define diagnosis criteria for these uncommon entities.

Keywords: Adenoid cystic carcinoma; Adénome des glandes mucineuses; Adénome des glandes muqueuses; Adénome pléiomorphe; Carcinome adénoïde kystique; Carcinome mucoépidermoïde; Carcinome épithélial-myoépithélial; Mucoepidermoid carcinoma; Mucous gland adenoma; Pleomorphic adenoma; Pulmonary salivary gland-type carcinoma; Tumeur de type glande salivaire du poumon.

Publication types

  • Review

MeSH terms

  • Adenocarcinoma / chemistry
  • Adenocarcinoma / classification*
  • Adenocarcinoma / diagnosis
  • Adenocarcinoma / pathology
  • Adenoma, Pleomorphic / chemistry
  • Adenoma, Pleomorphic / classification*
  • Adenoma, Pleomorphic / diagnosis
  • Adenoma, Pleomorphic / pathology
  • Biomarkers, Tumor
  • Carcinoma, Adenoid Cystic / chemistry
  • Carcinoma, Adenoid Cystic / classification
  • Carcinoma, Adenoid Cystic / diagnosis
  • Carcinoma, Adenoid Cystic / pathology
  • Carcinoma, Mucoepidermoid / chemistry
  • Carcinoma, Mucoepidermoid / classification
  • Carcinoma, Mucoepidermoid / diagnosis
  • Carcinoma, Mucoepidermoid / pathology
  • Cell Differentiation
  • Diagnosis, Differential
  • Humans
  • Lung Neoplasms / chemistry
  • Lung Neoplasms / classification*
  • Lung Neoplasms / diagnosis
  • Lung Neoplasms / pathology
  • Myoepithelioma / chemistry
  • Myoepithelioma / classification*
  • Myoepithelioma / diagnosis
  • Myoepithelioma / pathology
  • Prognosis
  • Salivary Glands / pathology

Substances

  • Biomarkers, Tumor