Hyperuricaemia in patients with type 2 diabetes in a tertiary healthcare centre in sub-Saharan Africa: prevalence and determinants

Trop Doct. 2016 Oct;46(4):216-221. doi: 10.1177/0049475515626030. Epub 2016 Jan 15.

Abstract

Hyperuricaemia in type 2 diabetes mellitus (T2DM) has been less well investigated in sub-Saharan Africans. Our study of 438 patients found that alcohol intake, body mass index ≥25 kg/m2, hydrochlorothiazide use, statin use, diabetic retinopathy and glomerular filtration rate <60 mL/min/1.73m2 were independently positively associated with hyperuricaemia; whereas smoking reduced this risk. Hyperuricaemia is strongly associated with some modifiable factors, diabetic complications and certain drugs. Our results suggest that further studies should evaluate the potential cost-benefit of screening for hyperuricaemia in type 2 diabetes.

Keywords: Cameroon; Hyperuricaemia; determinants; prevalence; type 2 diabetes mellitus.

MeSH terms

  • Aged
  • Biomarkers / blood
  • Black People / statistics & numerical data
  • Body Mass Index
  • Cameroon / epidemiology
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / blood
  • Diabetes Mellitus, Type 2 / epidemiology*
  • Diabetic Retinopathy / complications
  • Diabetic Retinopathy / epidemiology
  • Female
  • Humans
  • Hyperuricemia / blood*
  • Hyperuricemia / complications
  • Hyperuricemia / epidemiology
  • Male
  • Middle Aged
  • Prevalence
  • Risk Factors
  • Tertiary Care Centers
  • Tertiary Healthcare

Substances

  • Biomarkers