Protection from Cerebral Embolic Events During Transcatheter Aortic Valve Replacement

Charles F Rossow; James M McCabe

doi:10.1007/s11886-015-0692-7

Protection from Cerebral Embolic Events During Transcatheter Aortic Valve Replacement

Curr Cardiol Rep. 2016 Feb;18(2):16. doi: 10.1007/s11886-015-0692-7.

Authors

Charles F Rossow¹, James M McCabe²

Affiliations

¹ University of Washington, 1959 NE Pacific St, Box 356421, Seattle, WA, 98195, USA. rrossow@uw.edu.
² University of Washington, 1959 NE Pacific St, Box 356422, Seattle, WA, 98195, USA. jmmccabe@uw.edu.

PMID: 26768742
DOI: 10.1007/s11886-015-0692-7

Abstract

Transcatheter aortic valve replacement (TAVR) has been a major advancement in the treatment of high-risk patients with severe aortic stenosis. One of the primary concerns in applying this procedure to a broader patient population is the risk of embolic stroke. Cerebral emboli have been shown to originate from atheromatous plaques within the aorta and from the degenerate stenotic aortic valve itself. Thus, there has been significant interest in embolic protection devices designed to either filter or deflect potential cerebral emboli during TAVR. Here, we review the rationale and current data for embolic protection devices used during TAVR.

Keywords: Embolic protection; Stroke; TAVR; Transcatheter aortic valve replacement.

Publication types

Review

MeSH terms

Aortic Valve / physiopathology*
Aortic Valve Stenosis / physiopathology
Aortic Valve Stenosis / surgery*
Embolic Protection Devices*
Humans
Intracranial Embolism / prevention & control*
Risk Factors
Stroke / prevention & control*
Transcatheter Aortic Valve Replacement* / adverse effects
Transcatheter Aortic Valve Replacement* / methods
Treatment Outcome