Analysis of RUNX1 rearrangements: insights into leukaemogenesis mechanisms

Br J Haematol. 2016 Nov;175(4):738-740. doi: 10.1111/bjh.13881. Epub 2016 Jan 13.

Authors

Audrey Bidet¹, Elodie Laharanne¹, Sandrine Achard¹, Marina Migeon¹, Candice Moreau¹, Eric Lippert^{1

2}

Affiliations

¹ Laboratoire d'Hématologie, CHU de Bordeaux, Pessac Cedex, France.
² INSERM U1035, Laboratoire Hématopoïèse Leucémique et Cibles Thérapeutiques, Université de Bordeaux, Bordeaux, France.

PMID: 26765924
DOI: 10.1111/bjh.13881

No abstract available

Keywords: RUNX1 rearrangements; dominant negative transcripts; mutations; myeloid malignancies; unproductive transcripts.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Core Binding Factor Alpha 2 Subunit / genetics*
Core Binding Factor Alpha 2 Subunit / metabolism
Humans
Leukemia / genetics*

Substances

Core Binding Factor Alpha 2 Subunit