α1-Antitrypsin-primed tolerogenic dendritic cells prolong allograft kidney transplants survival in rats

Int Immunopharmacol. 2016 Feb:31:216-21. doi: 10.1016/j.intimp.2015.12.038. Epub 2016 Jan 4.

Authors

Guodong Chen¹, Jun Li¹, Lizhong Chen¹, Xingqiang Lai¹, Jiang Qiu²

Affiliations

¹ Division of Organ Transplantation, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China.
² Division of Organ Transplantation, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou 510080, China. Electronic address: Qiuj5100@126.com.

PMID: 26761724
DOI: 10.1016/j.intimp.2015.12.038

No abstract available

MeSH terms

Allografts / immunology
Animals
Cell Differentiation / drug effects
Cells, Cultured
Cytokines / metabolism
Dendritic Cells / drug effects
Dendritic Cells / immunology
Dendritic Cells / transplantation
Forkhead Transcription Factors / metabolism
Graft Rejection / prevention & control*
Graft Survival / drug effects*
Graft Survival / immunology
Immune Tolerance
Indoleamine-Pyrrole 2,3,-Dioxygenase / genetics
Indoleamine-Pyrrole 2,3,-Dioxygenase / metabolism
Kidney Transplantation*
Male
Rats
Rats, Inbred Lew
T-Lymphocytes, Regulatory / drug effects
T-Lymphocytes, Regulatory / immunology
alpha 1-Antitrypsin / pharmacology*

Substances

Cytokines
Forkhead Transcription Factors
Foxp3 protein, rat
Indoleamine-Pyrrole 2,3,-Dioxygenase
alpha 1-Antitrypsin