The concept of simplexity, as proposed by Alain Berthoz, is based on the assumption that solutions elaborated by living organisms to decipher and face complexity could be applicable to all complex adaptive systems. Within the pedagogical and didactic context the proposal of the French physiologist could provide a scientific research trajectory aiming at solving the tension between theory, praxis, descriptive approaches and practical needs. Thus, simplexity seems to be an operational strategy based on the identification of the principles that rule and guide the didactic action through patterns of adaptation, which allow to decipher complexity in terms of data elaboration and decision making among different opportunities.
Keywords: complexity; didactics; simplexity; trans-disciplinary.