DCD lung donation: donor criteria, procedural criteria, pulmonary graft function validation, and preservation

Transpl Int. 2016 Jul;29(7):790-7. doi: 10.1111/tri.12738. Epub 2016 Jan 15.

Abstract

In an era where there is a shortage of lungs for transplantation is increased utilization of lungs from donation after circulatory death (DCD) donors. We review the reports of 11 controlled and 1 uncontrolled DCD programs focusing on donor criteria, procedural criteria, graft assessment, and preservation techniques including the use of ex vivo lung perfusion. We have formulated conclusions and recommendations for each of these areas, which were presented at the 6th International Conference on Organ Donation. A table of recommendations, the grade of recommendations, and references are provided.

Keywords: donation after cardiac death; donation after circulatory death; guidelines; lung; nonheart beating donation; review.

Publication types

  • Review

MeSH terms

  • Adult
  • Brain Death
  • Congresses as Topic
  • Heparin / therapeutic use
  • Humans
  • International Cooperation
  • Lung Diseases / surgery*
  • Lung Transplantation / methods
  • Lung Transplantation / standards*
  • Middle Aged
  • Organ Preservation / methods*
  • Perfusion
  • Tissue Donors*
  • Tissue and Organ Procurement / methods
  • Tissue and Organ Procurement / standards*
  • Transplants
  • Warm Ischemia

Substances

  • Heparin