GOCART: GOlden-angle CArtesian randomized time-resolved 3D MRI

Yinghua Zhu; Yi Guo; Sajan Goud Lingala; R Marc Lebel; Meng Law; Krishna S Nayak

doi:10.1016/j.mri.2015.12.030

GOCART: GOlden-angle CArtesian randomized time-resolved 3D MRI

Magn Reson Imaging. 2016 Sep;34(7):940-50. doi: 10.1016/j.mri.2015.12.030. Epub 2015 Dec 19.

Authors

Yinghua Zhu¹, Yi Guo², Sajan Goud Lingala², R Marc Lebel³, Meng Law⁴, Krishna S Nayak²

Affiliations

¹ Ming Hsieh Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, USA. Electronic address: yinghuaz@usc.edu.
² Ming Hsieh Department of Electrical Engineering, Viterbi School of Engineering, University of Southern California, Los Angeles, USA.
³ Applied Science Laboratory, GE Healthcare, AB, Calgary, Canada; Foothills Medical Center, Calgary, Canada.
⁴ Department of Radiology, Keck School of Medicine, University of Southern California Medical Center, Los Angeles, USA.

PMID: 26707849
DOI: 10.1016/j.mri.2015.12.030

Abstract

Purpose: To develop and evaluate a novel 3D Cartesian sampling scheme which is well suited for time-resolved 3D MRI using parallel imaging and compressed sensing.

Methods: The proposed sampling scheme, termed GOlden-angle CArtesian Randomized Time-resolved (GOCART) 3D MRI, is based on golden angle (GA) Cartesian sampling, with random sampling of the ky-kz phase encode locations along each Cartesian radial spoke. This method was evaluated in conjunction with constrained reconstruction of retrospectively and prospectively undersampled in-vivo dynamic contrast enhanced (DCE) MRI data and simulated phantom data.

Results: In in-vivo retrospective studies and phantom simulations, images reconstructed from phase encodes defined by GOCART were equal to or superior to those with Poisson disc or GA sampling schemes. Typical GOCART sampling tables were generated in <100ms. GOCART has also been successfully utilized prospectively to produce clinically valuable whole-brain DCE-MRI images.

Conclusion: GOCART is a practical and efficient sampling scheme for time-resolved 3D MRI. It shows great potential for highly accelerated DCE-MRI and is well suited to modern reconstruction methods such as parallel imaging and compressed sensing.

Keywords: DCE; Dynamic golden angleRandomized samplingConstrained reconstruction; Time resolved 3D MRI.

MeSH terms

Algorithms
Brain / diagnostic imaging
Brain Neoplasms / diagnostic imaging*
Contrast Media
Humans
Image Enhancement / methods
Image Interpretation, Computer-Assisted / methods*
Imaging, Three-Dimensional / methods*
Magnetic Resonance Imaging / methods*
Phantoms, Imaging
Prospective Studies
Reproducibility of Results
Retrospective Studies
Sensitivity and Specificity

Substances

Contrast Media

Abstract

MeSH terms

Substances

Grants and funding