Multiple primary lung cancer (MPLC) is an uncommon entity of the primary lung cancer. With the widespread use of early detection tools such as multislice spiral computed tomography (CT), positron emission tomography (PET), and the better survival results after resection of primary lung cancer, more and more MPLC have been detected. However, the current diagnostic and therapeutic methods cannot meet the needs of MPLC individualized demand of diagnosis and treatment. At present, diagnostic criteria of MPLC are based on histological types, genetic characteristics, image features, tumor locations and clinical manifestation. On the treatment of MPLC, Surgery-based multi-discipline comprehensive treatment is regarded as the treatment of choice. In this paper, we make a review through summarizing the latest literature progress on the epidemiology, etiology, diagnostic criteria, treatment options and prognosis of MPLC.
多原发肺癌（multiple primary lung cancer, MPLC）是原发性肺癌的一种少见类型。随着多层螺旋计算机断层扫描（multislice spiral computed tomography, CT）及正电子发射体层显像（positron emission tomography, PET）等早期检查工具的广泛使用、原发性肺癌切除后生存率的提高，越来越多的MPLC被检出。但当前的诊断与治疗方法尚不能满足MPLC的个体化诊疗需求。目前MPLC在诊断方面主要依据肿瘤的组织学类型、遗传学特点、影像学特征、发生部位及临床表现来诊断，在治疗方面采取以手术为主的多学科综合治疗。本文总结最新的文献进展就MPLC的流行病学特征、病因、诊断、治疗及预后等方面做一综述。.