Articular manifestations in patients with Lyme disease

Reumatol Clin. 2016 Nov-Dec;12(6):327-330. doi: 10.1016/j.reuma.2015.10.013. Epub 2015 Dec 23.
[Article in English, Spanish]

Abstract

Objectives: To determine the percentage of Lyme patients with articular manifestations in NW Spain and to know their evolution and response to treatment.

Patients: A retrospective study (2006-2013) was performed using medical histories of confirmed cases of Lyme disease showing articular manifestations. Clinical and laboratory characteristics, together with the treatment and evolution of the patients, were analysed.

Results: Seventeen out of 108 LD confirmed patients (15.7%) showed articular manifestations. Regarding those 17 patients, 64.7%, 29.4% and 5.9% presented arthritis, arthralgia and bursitis, respectively. The knee was the most affected joint. Articular manifestations were often associated to neurological, dermatological and cardiac pathologies. Otherwise, most patients were in Stage III. The 11.8% of the cases progressed to a recurrent chronic arthritis despite the administration of an appropriate treatment.

Conclusions: Lyme disease patients showing articular manifestations should be included in the diagnosis of articular affections in areas of high risk of hard tick bite, in order to establish a suitable and early treatment and to avoid sequels.

Keywords: Articular manifestations; Diagnóstico diferencial; Differencial diagnosis; Enfermedad de Lyme; Lyme disease; Manifestaciones articulares; Tratamiento y evolución; Treatment and evolution.

Publication types

  • Observational Study

MeSH terms

  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Anti-Bacterial Agents / therapeutic use
  • Anti-Inflammatory Agents / therapeutic use
  • Child
  • Child, Preschool
  • Diagnosis, Differential
  • Disease Progression
  • Female
  • Humans
  • Joint Diseases / diagnosis
  • Joint Diseases / drug therapy
  • Joint Diseases / epidemiology
  • Joint Diseases / etiology*
  • Lyme Disease / complications*
  • Lyme Disease / diagnosis
  • Lyme Disease / drug therapy
  • Male
  • Middle Aged
  • Retrospective Studies
  • Spain
  • Treatment Outcome
  • Young Adult

Substances

  • Anti-Bacterial Agents
  • Anti-Inflammatory Agents