A Dual Sensor for pH and Hydrogen Peroxide Using Polymer-Coated Optical Fibre Tips

Malcolm S Purdey; Jeremy G Thompson; Tanya M Monro; Andrew D Abell; Erik P Schartner

doi:10.3390/s151229893

A Dual Sensor for pH and Hydrogen Peroxide Using Polymer-Coated Optical Fibre Tips

Sensors (Basel). 2015 Dec 17;15(12):31904-13. doi: 10.3390/s151229893.

Authors

Malcolm S Purdey^{1

2

3}, Jeremy G Thompson^{4

5

6}, Tanya M Monro^{7

8

9}, Andrew D Abell^{10

11

12}, Erik P Schartner^{13

14}

Affiliations

¹ ARC Centre of Excellence for Nanoscale BioPhotonics, Adelaide 5005, SA, Australia. malcolm.purdey@adelaide.edu.au.
² Institute for Photonics and Advanced Sensing (IPAS), The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. malcolm.purdey@adelaide.edu.au.
³ Discipline of Chemistry, School of Physical Sciences, The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. malcolm.purdey@adelaide.edu.au.
⁴ ARC Centre of Excellence for Nanoscale BioPhotonics, Adelaide 5005, SA, Australia. jeremy.thompson@adelaide.edu.au.
⁵ Institute for Photonics and Advanced Sensing (IPAS), The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. jeremy.thompson@adelaide.edu.au.
⁶ Robinson Research Institute, School of Medicine, The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. jeremy.thompson@adelaide.edu.au.
⁷ ARC Centre of Excellence for Nanoscale BioPhotonics, Adelaide 5005, SA, Australia. tanya.monro@unisa.edu.au.
⁸ Institute for Photonics and Advanced Sensing (IPAS), The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. tanya.monro@unisa.edu.au.
⁹ University of South Australia, North Terrace, Adelaide 5001, SA, Australia. tanya.monro@unisa.edu.au.
¹⁰ ARC Centre of Excellence for Nanoscale BioPhotonics, Adelaide 5005, SA, Australia. andrew.abell@adelaide.edu.au.
¹¹ Institute for Photonics and Advanced Sensing (IPAS), The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. andrew.abell@adelaide.edu.au.
¹² Discipline of Chemistry, School of Physical Sciences, The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. andrew.abell@adelaide.edu.au.
¹³ ARC Centre of Excellence for Nanoscale BioPhotonics, Adelaide 5005, SA, Australia. erik.schartner@adelaide.edu.au.
¹⁴ Institute for Photonics and Advanced Sensing (IPAS), The University of Adelaide, North Terrace, Adelaide 5005, SA, Australia. erik.schartner@adelaide.edu.au.

Abstract

This paper demonstrates the first single optical fibre tip probe for concurrent detection of both hydrogen peroxide (H₂O₂) concentration and pH of a solution. The sensor is constructed by embedding two fluorophores: carboxyperoxyfluor-1 (CPF1) and seminaphtharhodafluor-2 (SNARF2) within a polymer matrix located on the tip of the optical fibre. The functionalised fibre probe reproducibly measures pH, and is able to accurately detect H₂O₂ over a biologically relevant concentration range. This sensor offers potential for non-invasive detection of pH and H₂O₂ in biological environments using a single optical fibre.

Keywords: dual sensor; fibre tip sensor; hydrogen peroxide probe; optical fibre; pH sensor.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Fiber Optic Technology / methods*
Fluorescent Dyes / analysis
Fluorescent Dyes / chemistry*
Hydrogen Peroxide / analysis*
Hydrogen-Ion Concentration
Optical Fibers
Polymers / chemistry*

Substances

Fluorescent Dyes
Polymers
Hydrogen Peroxide