[Invasive neuromodulation in the treatment of drug-resistant epilepsies]

Orv Hetil. 2015 Dec 27;156(52):2103-9. doi: 10.1556/650.2015.30319.
[Article in Hungarian]

Abstract

Neuromodulation is one of the most developing new disciplines of medical science, which examines how electrical, chemical and mechanical interventions can modulate or change the functioning of the central and peripheral nervous system. Neuromodulation is a reversible form of therapy which uses electrical or mechanical stimulation or centrally-delivered drugs to modulate the abnormal function of the central nervous system in pain, spasticity, epilepsy, movement and psychiatric disorders, and certain cardiac, incontinency, visual and auditory diseases. Neuromodulation therapy has two major branches. Non-invasive neuromodulation includes transcranial magnetic simulation, direct current stimulation and transcutaneous electric nerve stimulation. Invasive neuromodulation includes deep brain stimulation, cortical stimulation, spinal cord stimulation, peripheral nerve stimulation, sacral nerve simulation, and subcutan stimulation. In this article the authors overview the apparently available neural interface technologies in epilepsy surgery.

Keywords: deep brain stimulation; epilepsy; epilepszia; gerincvelői ingerlés; mély agyi stimuláció; neuromodulation; neuromoduláció; responsive neurostimulation; reszponzív neurostimuláció; spinal cord stimulation; vagal nerve stimulation; vagusideg-stimuláció.

Publication types

  • English Abstract
  • Review

MeSH terms

  • Cerebral Cortex
  • Deep Brain Stimulation* / adverse effects
  • Deep Brain Stimulation* / instrumentation
  • Deep Brain Stimulation* / methods
  • Drug Resistant Epilepsy / physiopathology
  • Drug Resistant Epilepsy / therapy*
  • Evidence-Based Medicine
  • Humans
  • Peripheral Nerves
  • Randomized Controlled Trials as Topic
  • Spinal Cord
  • Thalamus
  • Transcranial Direct Current Stimulation* / adverse effects
  • Transcranial Direct Current Stimulation* / instrumentation
  • Transcranial Direct Current Stimulation* / methods
  • Transcutaneous Electric Nerve Stimulation* / adverse effects
  • Transcutaneous Electric Nerve Stimulation* / instrumentation
  • Transcutaneous Electric Nerve Stimulation* / methods
  • Vagus Nerve Stimulation* / adverse effects
  • Vagus Nerve Stimulation* / instrumentation
  • Vagus Nerve Stimulation* / methods