Complete Genome Sequence of Aneurinibacillus migulanus E1, a Gramicidin S- and d-Phenylalanyl-l-Propyl Diketopiperazine-Deficient Mutant

Lassaad Belbahri; Faizah N Alenezi; Lenka Luptakova; Mostafa E Rateb; Steve Woodward

doi:10.1128/genomeA.01441-15

Complete Genome Sequence of Aneurinibacillus migulanus E1, a Gramicidin S- and d-Phenylalanyl-l-Propyl Diketopiperazine-Deficient Mutant

Genome Announc. 2015 Dec 17;3(6):e01441-15. doi: 10.1128/genomeA.01441-15.

Authors

Lassaad Belbahri¹, Faizah N Alenezi², Lenka Luptakova³, Mostafa E Rateb⁴, Steve Woodward²

Affiliations

¹ Laboratory of Soil Biology, University of Neuchatel, Neuchâtel, Switzerland NextBiotech, Agareb, Tunisia lassaad.belbahri@unine.ch.
² NextBiotech, Agareb, Tunisia University of Aberdeen, Institute of Biological and Environment Science, Aberdeen, Scotland, United Kingdom.
³ Laboratory of Soil Biology, University of Neuchatel, Neuchâtel, Switzerland NextBiotech, Agareb, Tunisia University of Veterinary Med & Pharmacy, Institute of Biology, Zoology & Radiobiology, Department of Biology and Genetics, Košice, Slovakia.
⁴ School of Science & Sport, University of West of Scotland, Paisley, United Kingdom.

Abstract

We report here the complete genome sequence of the Aneurinibacillus migulanus E1 mutant deficient in gramicidin S (GS) and d-phenylalanyl-l-propyl diketopiperazine (DKP) formation. The genome consists of a circular chromosome (6,301,904 bp, 43.20% G+C content) without any plasmid. The complete genome sequence enables further investigation of the biosynthetic mechanism and the biological function of gramicidin S.