Biotransformation effects on anti lipogenic activity of citrus extracts

Food Chem. 2016 Apr 15:197 Pt B:1046-53. doi: 10.1016/j.foodchem.2015.11.109. Epub 2015 Nov 25.

Abstract

Citrus peel is a good source of flavonoids, with higher content in relation to pulp. This study proposed to investigate the anti-lipogenic potential of a newly developed citrus flavonoids extract, obtained from citrus industrial residue, bioprocessed in order to generate a commercial source of some flavonoids naturally found in low quantity. The results showed that the citrus peel extract obtained after biotransformation was a good source of hesperitin and naringenin, flavonoids that has no source for production on a large scale, as in supplements or medicines. Still, the results showed that all extracts could be used in obesity treatment. The original extract, "In Natura", would be useful to reduce new adipocytes synthesis and lipid accumulation, and the extract bioprocessed, "Biotransformed" extract could be used to induce lipolysis on fat tissue.

Keywords: Adipocytes; Biotransformation; Citrus peel extract; Hesperidin; Hesperidin (PubChem CID: 3594); Hesperitin; Hesperitin (PubChem CID: 72281); Lipolysis; Naringenin; Naringenin (PubChem CID: 932); Naringin; Naringin (PubChem CID: 74787988).

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Adipocytes / drug effects*
  • Animals
  • Citrus*
  • Flavanones / pharmacology*
  • Hesperidin / pharmacology*
  • Lipolysis / drug effects*
  • Mice
  • Plant Extracts / chemistry*
  • Plant Extracts / pharmacology

Substances

  • Flavanones
  • Plant Extracts
  • Hesperidin
  • naringenin
  • hesperetin