The prevalence of hydatid disease in human population and livestock, and the positive rate of echinococcal antigen in canine feces were analyzed with sample clustering method, according to the survey on hydatid disease in 72 counties in Gansu province in the database of the National Survey on Prevalence of Echinococcosis in 2012. The prevalence of hydatid disease in huma and livestock, and the positive rate of echinococcal antigen in canine feces were 0-1.59%, 0-15.22%, and 0-16.87% respectively. Clustering analysis revealed four types of prevalence in the 72 counties. The first type existed only in Dunhuang city, with the three indicators being 0.27%, 15.22% and 16.87%; the second in four counties, with the three indicators being 0.43%, 6.57% and 1.83%; the third in 22 counties, with the three indicators being 0.22%, 1.15% and 1035%; and the fourth in 45 counties, with the three indicators being 0.16%, 0.58% and 1.69%.