Cardiovascular Tissue Engineering: Preclinical Validation to Bedside Application

Physiology (Bethesda). 2016 Jan;31(1):7-15. doi: 10.1152/physiol.00018.2015.

Abstract

Advancements in biomaterial science and available cell sources have spurred the translation of tissue-engineering technology to the bedside, addressing the pressing clinical demands for replacement cardiovascular tissues. Here, the in vivo status of tissue-engineered blood vessels, heart valves, and myocardium is briefly reviewed, illustrating progress toward a tissue-engineered heart for clinical use.

Publication types

  • Research Support, N.I.H., Extramural
  • Review

MeSH terms

  • Animals
  • Biocompatible Materials / therapeutic use*
  • Cardiovascular System / physiopathology*
  • Humans
  • Tissue Engineering*

Substances

  • Biocompatible Materials