Ebola vaccine R&D: Filling the knowledge gaps

Sci Transl Med. 2015 Dec 9;7(317):317ps24. doi: 10.1126/scitranslmed.aad3106.

Abstract

With an emphasis on systems analyses, the VSV-EBOVAC project harnesses state-of-the-art technologies that illuminate mechanisms behind the observed immunogenicity and reactogenicity of the rVSV-ZEBOV vaccine and ensures that such information is shared among stakeholders.

Trial registration: ClinicalTrials.gov NCT02283099 NCT02287480 NCT02296983.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Antibody Formation / immunology
  • Clinical Trials as Topic
  • Ebola Vaccines / immunology*
  • Ebolavirus / immunology
  • Humans
  • Knowledge*
  • Research*
  • Vaccination

Substances

  • Ebola Vaccines

Associated data

  • ClinicalTrials.gov/NCT02283099
  • ClinicalTrials.gov/NCT02287480
  • ClinicalTrials.gov/NCT02296983
  • PACTR/PACTR2014000089322
  • PACTR/PACTR201503001057193