Keratocystic Odontogenic Tumour with Extraosseal Spread: Evaluation of the Effect Carnoy's Solution

Prague Med Rep. 2015;116(4):303-13. doi: 10.14712/23362936.2015.69.

Abstract

Keratocystic odontogenic tumour is relatively rare benign tumour. It is characterized by its fast aggressive growth and high risk of recurrence. Treatment is always surgical: conservative (enucleation, marsupialization) or aggressive (enucleation followed by application of Carnoy's solution, cryotherapy; peripheral ostectomy or en block resection of the jaw). Authors analysed retrospectively 22 patients who fulfilled inclusion criteria, i.e. had odontogenic keratocystic tumour of mandible, wherein antero-posterior dimension was at least 30 mm, and the tumour penetrated into the surrounding soft tissues. All patients underwent tumour enucleation, in 11 patients Carnoy's solution was given into the bone cavity after enucleation. The recurrence rate in the evaluation at least 36 months after surgery was both patient groups the same: 45.4%.

Keywords: Carnoy’s solution; Enucleation; Keratocystic odontogenic tumour; Recurrence.

MeSH terms

  • Acetic Acid / therapeutic use*
  • Adolescent
  • Adult
  • Aged
  • Aged, 80 and over
  • Child
  • Chloroform / therapeutic use*
  • Ethanol / therapeutic use*
  • Female
  • Fixatives*
  • Humans
  • Male
  • Mandibular Neoplasms / pathology
  • Mandibular Neoplasms / therapy*
  • Middle Aged
  • Odontogenic Tumors / pathology
  • Odontogenic Tumors / therapy*
  • Retrospective Studies
  • Young Adult

Substances

  • Carnoy's solution
  • Fixatives
  • Ethanol
  • Chloroform
  • Acetic Acid