Two Photon Induced Luminescence of BSA Protected Gold Clusters

Sangram L Raut; Dmytro Shumilov; Rahul Chib; Ryan Rich; Zygmunt Gryczynski; Ignacy Gryczynski

doi:10.1016/j.cplett.2013.01.028

Two Photon Induced Luminescence of BSA Protected Gold Clusters

Chem Phys Lett. 2013 Mar 13:561-562:74-76. doi: 10.1016/j.cplett.2013.01.028.

Authors

Sangram L Raut¹, Dmytro Shumilov², Rahul Chib¹, Ryan Rich¹, Zygmunt Gryczynski³, Ignacy Gryczynski⁴

Affiliations

¹ Center for Commercialization of Fluorescence Technologies, University of North Texas Health Science Center, 3500 Camp Bowie Blvd. Fort Worth, Texas, USA, 76107.
² Department of Physics. Texas Christian University, 2800 S. University Dr., Fort Worth, Texas, USA, 76129.
³ Center for Commercialization of Fluorescence Technologies, University of North Texas Health Science Center, 3500 Camp Bowie Blvd. Fort Worth, Texas, USA, 76107 ; Department of Physics. Texas Christian University, 2800 S. University Dr., Fort Worth, Texas, USA, 76129.
⁴ Center for Commercialization of Fluorescence Technologies, University of North Texas Health Science Center, 3500 Camp Bowie Blvd. Fort Worth, Texas, USA, 76107 ; Department of Cell Biology and Anatomy, University of North Texas Health Science Center. 3500 Camp Bowie Blvd. Fort Worth, Texas, USA, 76107.

Abstract

In this short letter, we have synthesized the BSA protected Au₂₅ nanoclusters and studied their two photon luminescence behavior. We demonstrate that BSA Au₂₅ nanoclusters can be used as a probe with two photon excitation capability. Our results show a quadratic relation between excitation power and emission intensity whereas with one photon excitation shows a linear dependence. The emission spectrum of BSA Au₂₅ nanoclusters with one photon and two photon excitation shows no appreciable change. Due to its long wavelength emission (650 nm) and two photon excitation, BSA Au₂₅ can be potentially used as a probe for deep tissue imaging.

Keywords: BSA; Gold clusters; Luminescence; One and two photon excitation.

Grants and funding

R01 EB012003/EB/NIBIB NIH HHS/United States