Abstract
Freezing of gait (FOG) is a heterogeneous symptom. Studies of treatment for FOG are scarce. Levodopa and monoamine oxidase inhibitors (rasagiline and selegiline) have shown effective improvement for FOG. Other drugs, such as L-threo-3, 4-dihydroxyphenylserine, amantadine, and botulinum toxin have exhibited some beneficial effects. The present review summarizes the potential drug treatment for FOG in Parkinsonism.
Publication types
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Research Support, Non-U.S. Gov't
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Review
MeSH terms
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Aged
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Aged, 80 and over
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Amantadine / therapeutic use
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Antiparkinson Agents / therapeutic use*
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Botulinum Toxins / therapeutic use
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Droxidopa / therapeutic use
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Gait Disorders, Neurologic / drug therapy*
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Gait Disorders, Neurologic / etiology
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Humans
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Indans / therapeutic use
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Levodopa / therapeutic use*
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Methylphenidate / therapeutic use
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Middle Aged
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Monoamine Oxidase Inhibitors / therapeutic use*
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Parkinsonian Disorders / complications*
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Selegiline / therapeutic use
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Treatment Outcome
Substances
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Antiparkinson Agents
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Indans
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Monoamine Oxidase Inhibitors
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rasagiline
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Methylphenidate
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Selegiline
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Levodopa
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Amantadine
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Botulinum Toxins
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Droxidopa