STAT1 activation in association with JAK2 exon 12 mutations

Haematologica. 2016 Jan;101(1):e15-9. doi: 10.3324/haematol.2015.128546. Epub 2015 Dec 3.

¹ Cambridge Institute for Medical Research and Wellcome Trust/MRC Stem Cell Institute, University of Cambridge, UK Department of Haematology, Addenbrooke's Hospital, UK Department of Haematology, University of Cambridge, Cambridge, UK.
² Cambridge Institute for Medical Research and Wellcome Trust/MRC Stem Cell Institute, University of Cambridge, UK Department of Haematology, University of Cambridge, Cambridge, UK.
³ Hematology Department, Hospital del Mar-IMIM, Barcelona, Spain.
⁴ Department of Experimental and Clinical Medicine, University of Florence and Azienda Ospedaliera Universitaria Careggi, Florence, Italy.
⁵ Department of Haematology, Guy's and St Thomas' NHS Foundation Trust, London, UK.
⁶ Department of Haematology, Royal Hallamshire Hospital, Sheffield, UK.
⁷ University Hospital of Ulm, Department of Internal Medicine III, Germany.
⁸ Institut Bergonie, Department of Hematology, Bordeaux, France.
⁹ Laboratoire d'Hematologie, CHU de Bordeaux and Laboratorie Hematopoiese Leucemique et Cibles Thérapeutiques, INSERM U 1035, Universite Bordeaux Segalen, Bordeaux, France.
¹⁰ University of Bordeaux, Etablissement Français du Sang, France.
¹¹ Cambridge Institute for Medical Research and Wellcome Trust/MRC Stem Cell Institute, University of Cambridge, UK Department of Haematology, Addenbrooke's Hospital, UK Department of Haematology, University of Cambridge, Cambridge, UK arg1000@cam.ac.uk.

No abstract available

Keywords: JAK2 exon 12; STAT1; activation; mutations.

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