Efavirenz as a cause of ataxia in children

S Afr Med J. 2015 Nov;105(11):897-8. doi: 10.7196/SAMJ.2015.v105i11.9451.

Abstract

Acute ataxia in childhood is often caused by toxin ingestion. With the increasing number of paediatric patients on antiretroviral medication, we are seeing more side-effects of these drugs. We report two cases of efavirenz toxicity causing ataxia.

Publication types

  • Case Reports

MeSH terms

  • Adolescent
  • Alkynes
  • Anti-HIV Agents / adverse effects*
  • Anti-HIV Agents / blood
  • Ataxia / chemically induced*
  • Benzoxazines / adverse effects*
  • Benzoxazines / blood
  • Child
  • Cyclopropanes
  • Female
  • HIV Infections / drug therapy*
  • HIV Seropositivity / drug therapy
  • Humans

Substances

  • Alkynes
  • Anti-HIV Agents
  • Benzoxazines
  • Cyclopropanes
  • efavirenz