Toward Network Biology in E. coli Cell

Hirotada Mori; Rikiya Takeuchi; Yuta Otsuka; Steven Bowden; Katsushi Yokoyama; Ai Muto; Igor Libourel; Barry L Wanner

doi:10.1007/978-3-319-23603-2_9

Toward Network Biology in E. coli Cell

Adv Exp Med Biol. 2015:883:155-68. doi: 10.1007/978-3-319-23603-2_9.

Authors

Hirotada Mori¹, Rikiya Takeuchi², Yuta Otsuka³, Steven Bowden⁴, Katsushi Yokoyama⁵, Ai Muto⁶, Igor Libourel⁷, Barry L Wanner⁸

Affiliations

¹ Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Naras, 630-0101, Japan. hmori@gtc.naist.jp.
² Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Naras, 630-0101, Japan. takeriki0502@gmail.com.
³ Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Naras, 630-0101, Japan. y-otsuka@bs.naist.jp.
⁴ Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Naras, 630-0101, Japan. sbowden@umn.edu.
⁵ Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Naras, 630-0101, Japan. k.yokoyama@hamayaku.ac.jp.
⁶ Graduate School of Biological Sciences, Nara Institute of Science and Technology, 8916-5 Takayama, Ikoma, Naras, 630-0101, Japan. muto@bs.naist.jp.
⁷ The Biotechnology Institute, University of Minnesota, 1479 Gortner Avenue, St. Paul, MN, 55108-6106, USA. libourel@umn.eud.
⁸ Department of Biological Sciences, Purdue University, West Lafayette, IN, 47907, USA. blwanner@genetics.med.harvard.edu.

PMID: 26621467
DOI: 10.1007/978-3-319-23603-2_9

Abstract

E. coli has been a critically important model research organism for more than 50 years, particularly in molecular biology. In 1997, the E. coli draft genome sequence was published. Post-genomic techniques and resources were then developed that allowed E. coli to become a model organism for systems biology. Progress made since publication of the E. coli genome sequence will be summarized.

Keywords: E. coli; Network biology; Plasmid clone libraries.

Publication types

Research Support, Non-U.S. Gov't
Review

MeSH terms

Computational Biology*
Escherichia coli / genetics*
Gene Library
High-Throughput Screening Assays