[Assessment of 2 automated microdilution techniques compared to an agar dilution method in determining sensitivity to fosfomycin in strains of carbapenem-resistant Pseudomonas aeruginosa]

Enferm Infecc Microbiol Clin. 2016 Aug-Sep;34(7):406-8. doi: 10.1016/j.eimc.2015.09.019. Epub 2015 Nov 25.
[Article in Spanish]

Abstract

Carbapenems-resistance in Pseudomonas aeruginosa isolates has been widely reported. Fosfomycin has been shown to act synergistically with other antimicrobials. The agar dilution method was approved for susceptibility testing for fosfomycin and Pseudomonas aeruginosa. However, broth microdilution methods are the basis of systems currently used in clinical microbiology laboratories. The results of this study indicate that these methods are acceptable as susceptibility testing methods for fosfomycin against these organisms.

Keywords: Fosfomicina; Fosfomycin; Pseudomonas aeruginosa; Sensibilidad; Susceptibility.

Publication types

  • Comparative Study
  • Evaluation Study

MeSH terms

  • Agar
  • Anti-Bacterial Agents / pharmacology*
  • Carbapenems / pharmacology*
  • Disk Diffusion Antimicrobial Tests
  • Drug Resistance, Bacterial
  • Fosfomycin / pharmacology*
  • Humans
  • Pseudomonas aeruginosa / drug effects*

Substances

  • Anti-Bacterial Agents
  • Carbapenems
  • Fosfomycin
  • Agar