Medibots: Dual-Action Biogenic Microdaggers for Single-Cell Surgery and Drug Release

Sarvesh Kumar Srivastava; Mariana Medina-Sánchez; Britta Koch; Oliver G Schmidt

doi:10.1002/adma.201504327

Medibots: Dual-Action Biogenic Microdaggers for Single-Cell Surgery and Drug Release

Adv Mater. 2016 Feb 3;28(5):832-7. doi: 10.1002/adma.201504327. Epub 2015 Nov 30.

Authors

Sarvesh Kumar Srivastava¹, Mariana Medina-Sánchez¹, Britta Koch¹, Oliver G Schmidt¹

Affiliation

¹ Institute for Integrative Nanosciences, IFW Dresden, Helmholtzstraße 20, 01069, Dresden, Germany.

PMID: 26619085
DOI: 10.1002/adma.201504327

Abstract

An innovative concept for the fabrication of dual-action microrobots capable of performing single-cell microsurgery along with a site-directed drug-delivery feature is presented. These multi-action plant-derived biocompatible "medibots" can play a pivotal role in understanding micromotor interactions at the cellular level, aiming toward the destruction of harmful cells (like cancer) among others in living systems.

Keywords: biogenic micromotors; cancer treatments; drug delivery; microdrilling; non-invasive microsurgery.