Computational study of the fluid-dynamics in carotids before and after endarterectomy

J Biomech. 2016 Jan 4;49(1):26-38. doi: 10.1016/j.jbiomech.2015.11.009. Epub 2015 Nov 18.

Abstract

In this work, we provide a computational study of the effects of carotid endarterectomy (CEA) on the fluid-dynamics at internal carotid bifurcations. We perform numerical simulations in real geometries of the same patients before and after CEA, using patient-specific boundary data obtained by Echo-Color Doppler measurements. We analyze four patients with a primary closure and other four where a patch was used to close arteriotomies. The results show that (i) CEA is able to restore physiological fluid-dynamic conditions; (ii) among the post-operative cases, the presence of patch leads to local hemodynamic conditions which might imply a higher risk of restenosis in comparison with the cases without patch.

Keywords: CFD; Carotids; Endarterectomy; Restenosis.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Blood Vessel Prosthesis
  • Carotid Artery, Internal / surgery*
  • Carotid Stenosis / physiopathology*
  • Computer Simulation
  • Coronary Restenosis / physiopathology*
  • Endarterectomy, Carotid*
  • Female
  • Heart Valve Diseases / surgery
  • Hemodynamics
  • Humans
  • Hydrodynamics
  • Male
  • Models, Theoretical
  • Polyethylene Terephthalates
  • Treatment Outcome
  • Ultrasonography, Doppler

Substances

  • Polyethylene Terephthalates