Current Clinical Applications of Testicular Cancer Biomarkers

Maria C Mir; Nicola Pavan; Mark L Gonzalgo

doi:10.1016/j.ucl.2015.08.011

Current Clinical Applications of Testicular Cancer Biomarkers

Urol Clin North Am. 2016 Feb;43(1):119-25. doi: 10.1016/j.ucl.2015.08.011.

Authors

Maria C Mir¹, Nicola Pavan², Mark L Gonzalgo³

Affiliations

¹ Department of Urology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA.
² Department of Urology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA; Department of Medical, Surgical and Health Science, Urology Clinic, University of Trieste, Trieste, Italy.
³ Department of Urology, Sylvester Comprehensive Cancer Center, University of Miami Miller School of Medicine, Miami, FL 33136, USA. Electronic address: m.gonzalgo@miami.edu.

PMID: 26614034
DOI: 10.1016/j.ucl.2015.08.011

Abstract

Current use of testicular biomarkers for screening, diagnosis, and follow-up is reviewed in the context of potential clinical utility of these tests. This information will be of value to clinicians to determine patient suitability for certain treatments and will also assist in reviewing current literature regarding potential biomarkers that may be used for testicular cancer.

Keywords: Markers; Mitochondrial DNA; Serum; Testicular germ cell tumors; Tumor markers; microRNAs.

Publication types

Review

MeSH terms

Biomarkers, Tumor / blood*
Humans
Male
MicroRNAs / blood
Neoplasms, Germ Cell and Embryonal / blood*
Prognosis
Testicular Neoplasms / diagnosis*
Testicular Neoplasms / therapy*

Substances

Biomarkers, Tumor
MicroRNAs