1 Department of Psychiatry, College of Medicine and Hospital, National Cheng Kung University, Tainan, Taiwan ; Institute of Behavioral Medicine, College of Medicine, National Cheng Kung University, Tainan, Taiwan ; Institute of Allied Health Sciences, College of Medicine, National Cheng Kung University, Tainan, Taiwan ; Addiction Research Center, National Cheng Kung University, Tainan, Taiwan ; Center for Neuropsychiatric Research, National Health Research Institutes, Miaoli, Taiwan.