Hepatitis C: An Eastern Perspective

Gastroenterol Clin North Am. 2015 Dec;44(4):793-805. doi: 10.1016/j.gtc.2015.07.007. Epub 2015 Sep 16.

Abstract

HCV in the East is a complex scenario with prevalence rates of 0.5% to as high as 4.7%, and variable distributions of genotypes, with a dominance of genotype 1b in East Asia, genotype 3 in South Asia and South East Asia, and genotype 6 in Indochina. Approvals for the new oral directing antiviral agents (DAAs), in the East have been very slow, but ultimately will be achieved by 2019, consequently, pegylated interferon and ribavirin are still widely used. Nonetheless the main issues are the problems of screening and linkage to management, and the considerable barriers to access HCV care.

Keywords: Asia; Cost-effectiveness; Hepatitis C; Roadmap strategy.

Publication types

  • Review

MeSH terms

  • Antiviral Agents / economics
  • Antiviral Agents / therapeutic use*
  • Asia / epidemiology
  • Cost-Benefit Analysis
  • Genotype
  • Health Policy
  • Health Services Accessibility
  • Hepacivirus / genetics*
  • Hepatitis C, Chronic* / drug therapy
  • Hepatitis C, Chronic* / economics
  • Hepatitis C, Chronic* / epidemiology
  • Hepatitis C, Chronic* / virology
  • Humans

Substances

  • Antiviral Agents