HeartWare left ventricular assist device for the treatment of advanced heart failure

Future Cardiol. 2016 Jan;12(1):17-26. doi: 10.2217/fca.15.58. Epub 2015 Nov 24.

Abstract

The importance of mechanical circulatory support in the therapy of advanced heart failure is steadily growing. The rapid developments in the field of mechanical support are characterized by continuous miniaturization and enhanced performance of the assist devices, providing increased pump durability and prolonged patient survival. The HeartWare left ventricular assist device system (HeartWare Inc., Framingham, MA, USA) is a mechanical ventricular assist device with over 8000 implantations worldwide. Compared with other available assist devices it is smaller in size and used in a broad range of patients. The possibility of minimally invasive procedures is one of the major benefits of the device - allowing implants and explants, as well as exchanges of the device with reduced surgical impact. We present here a review of the existing literature on the treatment of advanced heart failure using the HeartWare left ventricular assist device system.

Keywords: cardiac surgery; implantation techniques; left ventricular assist device; minimal-invasive surgery; ventricular assist device.

Publication types

  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Anticoagulants / therapeutic use
  • Clinical Trials as Topic
  • Gastrointestinal Hemorrhage / chemically induced
  • Heart Failure / surgery*
  • Heart-Assist Devices* / adverse effects
  • Humans
  • Minimally Invasive Surgical Procedures
  • Prosthesis Implantation / methods
  • Quality of Life
  • Sternotomy
  • Stroke / etiology
  • Stroke / prevention & control
  • Survival Analysis
  • Thrombosis / etiology
  • Thrombosis / prevention & control

Substances

  • Anticoagulants