What We Can Learn from "Super-responders"

Card Electrophysiol Clin. 2015 Dec;7(4):781-8. doi: 10.1016/j.ccep.2015.08.019.

Abstract

This review discusses the state of the art of knowledge to help decision making in patients who are candidates for cardiac resynchronization therapy (CRT) and to analyze the long-term total and cardiac mortality, sudden death, and CRT with a defibrillator intervention rate, as well as the evolution of echocardiographic parameters in patients with a left ventricular (LV) ejection fraction of greater than 50% after CRT implantation. Owing to normalization of LV function in super-responders, the need for a persistent defibrillator backup is also considered.

Keywords: CRT; Cardiac resynchronization therapy; Left ventricular ejection fraction; Left ventricular function.

Publication types

  • Meta-Analysis
  • Review

MeSH terms

  • Cardiac Resynchronization Therapy / methods
  • Cardiac Resynchronization Therapy / mortality
  • Cardiac Resynchronization Therapy / statistics & numerical data*
  • Clinical Decision-Making / methods
  • Combined Modality Therapy / methods
  • Combined Modality Therapy / mortality
  • Combined Modality Therapy / statistics & numerical data
  • Comorbidity
  • Defibrillators, Implantable / statistics & numerical data*
  • Evidence-Based Medicine
  • Heart Failure / mortality*
  • Heart Failure / prevention & control*
  • Humans
  • Patient Selection
  • Recovery of Function
  • Risk Factors
  • Surveys and Questionnaires
  • Survival Analysis
  • Treatment Outcome
  • Ventricular Dysfunction, Left / mortality*
  • Ventricular Dysfunction, Left / prevention & control*