Neurosarcoidosis

Clin Chest Med. 2015 Dec;36(4):643-56. doi: 10.1016/j.ccm.2015.08.007. Epub 2015 Sep 26.

Abstract

Neurosarcoidosis is known as the great mimicker and may appear similar to lymphoma, multiple sclerosis, and other diseases affecting the nervous system. Although definitive diagnosis requires histologic confirmation of the affected neural tissue, characteristic clinical manifestations, gadolinium-enhanced MRI patterns and specific cerebrospinal fluid findings can help support the diagnosis in the absence of neural biopsy. An understanding of the common clinical presentations and diagnostic findings is central to the evaluation and management of neurosarcoidosis.

Keywords: Cranial neuropathy; Meningitis; Myelopathy; Neurosarcoidosis; Sarcoidosis.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Adult
  • Biopsy
  • Central Nervous System Diseases*
  • Disease Management
  • Humans
  • Magnetic Resonance Imaging / methods*
  • Male
  • Sarcoidosis / complications*

Supplementary concepts

  • Neurosarcoidosis