A transcriptome resource for common carp after growth hormone stimulation

Mar Genomics. 2016 Feb:25:25-27. doi: 10.1016/j.margen.2015.11.004. Epub 2015 Nov 14.

Abstract

Growth is one of the most important phenotypes for aquaculture and is thus a subject of great interest for researchers. Growth hormone (GH) is a key peptide controlling the growth of various fish species. To understand transcriptome changes induced by GH, common carp was injected with 2 μg/g GH and tissue isolated after 6h. RNA-Seq was performed to estimate the effects of GH on gene expression in hepatic tissues. The results revealed that GH regulated the expression of multiple genes, including those related to cell growth, sexual development and immune system processes. These data show that GH affects various physiological activities by regulating gene expression, and provides a useful resource for studying common carp.

Keywords: Common carp; Growth hormone; Liver; Transcriptome.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Animals
  • Carps / genetics
  • Carps / metabolism*
  • Gene Expression Regulation / drug effects*
  • Gene Expression Regulation / immunology
  • Growth Hormone / pharmacology*
  • Sexual Maturation / genetics
  • Sexual Maturation / physiology
  • Transcriptome

Substances

  • Growth Hormone