Simultaneous sonochemical-enzymatic coating of medical textiles with antibacterial ZnO nanoparticles

Ultrason Sonochem. 2016 Mar:29:244-50. doi: 10.1016/j.ultsonch.2015.09.021. Epub 2015 Oct 20.

Abstract

The antimicrobial finishing is a must for production of medical textiles, aiming at reducing the bioburden in clinical wards and consequently decreasing the risk of hospital-acquired infections. This work reports for the first time on a simultaneous sonochemical/enzymatic process for durable antibacterial coating of cotton with zinc oxide nanoparticles (ZnO NPs). The novel technology goes beyond the "stepwise" concept we proposed recently for enzymatic pre-activation of the fabrics and subsequent sonochemical nano-coating, and is designed to produce "ready-to-use" antibacterial medical textiles in a single step. A multilayer coating of uniformly dispersed NPs was obtained in the process. The enzymatic treatment provides better adhesion of the ZnO NPs and, as a consequence, enhanced coating stability during exploitation. The NPs-coated cotton fabrics inhibited the growth of the medically relevant Staphylococcus aureus and Escherichia coli respectively by 67% and 100%. The antibacterial efficiency of these textile materials resisted the intensive laundry regimes used in hospitals, though only 33% of the initially deposited NPs remained firmly fixed onto the fabrics after multiple washings.

Keywords: Antibacterial coatings; Cellulase; Medical textiles; Nanoparticles; Sonochemistry; Zinc oxide.

Publication types

  • Research Support, Non-U.S. Gov't

MeSH terms

  • Anti-Bacterial Agents / chemistry
  • Anti-Bacterial Agents / pharmacology
  • Biocatalysis
  • Cellulase / metabolism*
  • Cotton Fiber*
  • Escherichia coli / drug effects
  • Industry
  • Nanoparticles / chemistry*
  • Staphylococcus aureus / drug effects
  • Ultrasonic Waves*
  • Zinc Oxide / chemistry*
  • Zinc Oxide / pharmacology*

Substances

  • Anti-Bacterial Agents
  • Cellulase
  • Zinc Oxide