Postirradiation Leiomyosarcoma of Rectum Presenting as a Polyp: Case Report and Review of the Literature

Int J Surg Pathol. 2016 Apr;24(2):163-9. doi: 10.1177/1066896915617025. Epub 2015 Nov 18.

Abstract

Radiation-induced leiomyosarcomas of the gastrointestinal tract are rare. Very few cases have been documented to date. The histological similarity to gastrointestinal stromal tumor has raised doubts if many of the cases originally reported to be leiomyosarcoma before the widespread use of CD117 were indeed gastrointestinal stromal tumors. We present a case of post-irradiation leiomyosarcoma presenting as a rectal polyp and review the literature.

Keywords: leiomyosarcoma of rectum; radiation-induced sarcoma; rectal polyp.

Publication types

  • Case Reports
  • Review

MeSH terms

  • Female
  • Humans
  • Leiomyosarcoma / pathology*
  • Middle Aged
  • Neoplasms, Radiation-Induced / pathology*
  • Neoplasms, Second Primary / pathology*
  • Polyps / pathology
  • Rectal Neoplasms / pathology*
  • Uterine Cervical Neoplasms / radiotherapy