OVERVIEW OF A DIGITAL TOMOSYNTHESIS DEVELOPMENT: NEW APPROACHES FOR LOW-DOSE CHEST IMAGING

Radiat Prot Dosimetry. 2016 Jun;169(1-4):171-6. doi: 10.1093/rpd/ncv469. Epub 2015 Nov 12.

Abstract

Lung cancer has the highest mortality rate among all cancer types, and it has especially high occurrence in Hungary. Low-dose computed tomography (LDCT) has been proved to be a beneficial screening method for lung cancer, decreasing the mortality rate by 20 %. Because of the intensifying fears from X-ray radiation, there is a need to develop other modalities that might work with less radiation and have similar sensitivity in lung nodule finding. Digital tomosynthesis (DTS) may be such a modality that can be a real alternative to LDCT. The goal of this article is to summarise the first results of a Hungarian project for developing a DTS system extended with a computer-aided detection system. It describes the main approaches applied and the main benefits of using DTS based on the first clinical examinations.

MeSH terms

  • Algorithms
  • Constriction, Pathologic / diagnostic imaging
  • Diagnosis, Computer-Assisted / methods*
  • False Positive Reactions
  • Humans
  • Hungary
  • Lung Neoplasms / diagnostic imaging*
  • Radiographic Image Enhancement / methods*
  • Radiography, Thoracic / methods*
  • Sensitivity and Specificity
  • Thorax / diagnostic imaging
  • Tomography, X-Ray Computed / methods*
  • X-Rays