Asteatotic dermatitis (AsD) is a common skin disease characterized by dry skin, itching, erythema, peeling and other skin lesions. It results from the damage in cutaneous barrier related to age, seasonal climate and bathing habits, and presents dysfunction of sebaceous, sweat glands and the increase of transepidermal water loss. The pathogenesis of AsD is not clear. Previous studies mainly focused on the relationship between skin barrier damage and bathing habits, age or gender. Recently, more studies focus on its relationship with other systematic diseases and drugs. This paper reviews etiology and pathogenesis of AsD to provide new ideas for the diagnosis and treatment of AsD.
乏脂性皮炎是一种因年龄、季节气候、洗浴习惯等因素引起皮肤屏障受破坏、脂质与汗腺分泌功能失调、经皮水分丢失过多, 而出现皮肤干燥、瘙痒、红斑、脱皮等临床表现的皮肤疾病, 广泛存在于人群中.乏脂性皮炎的发病机制并不明确, 过去的研究重视该病与洗浴习惯、季节和年龄、性别导致皮肤屏障破坏的关系, 但近年来的研究趋向于探索该病与各种其他系统疾病、药物之间的关系.本文就乏脂性皮炎的病因和发病机制进行综述, 旨在为临床诊断和治疗提供新的思路.