Abstract
Two new abietane diterpenoid glycosides, named clinopoditerpenes B (1) and C (2), were isolated from Clinopodium chinese. The structures of the new compounds were determined on the basis of extensive spectral analysis. Compound 1 exhibited cardioprotective effect against H2O2-induced apoptosis in H9c2 cells.
Keywords:
Clinopodium chinese; cardioprotective effect; diterpenoid glycoside.
Publication types
-
Research Support, Non-U.S. Gov't
MeSH terms
-
Abietanes / chemistry
-
Abietanes / pharmacology*
-
Apoptosis / drug effects
-
Cardiotonic Agents / chemistry
-
Cardiotonic Agents / pharmacology*
-
Cell Line
-
Drugs, Chinese Herbal / chemistry
-
Glycosides / chemistry*
-
Glycosides / isolation & purification*
-
Humans
-
Hydrogen Peroxide / toxicity*
-
Lamiaceae / chemistry*
-
Plant Extracts / analysis
-
Spectrometry, Mass, Electrospray Ionization
Substances
-
Abietanes
-
Cardiotonic Agents
-
Drugs, Chinese Herbal
-
Glycosides
-
Plant Extracts
-
clinopoditerpene B
-
clinopoditerpene C
-
Hydrogen Peroxide