Plasmodium knowlesi as a Threat to Global Public Health

Korean J Parasitol. 2015 Oct;53(5):575-81. doi: 10.3347/kjp.2015.53.5.575. Epub 2015 Oct 29.

Abstract

Malaria is a tropical disease caused by protozoans of the Plasmodium genus. Delayed diagnosis and misdiagnosis are strongly associated with higher mortality. In recent years, a greater importance is attributed to Plasmodium knowlesi, a species found mainly in Southeast Asia. Routine parasitological diagnostics are associated with certain limitations and difficulties in unambiguous determination of the parasite species based only on microscopic image. Recently, molecular techniques have been increasingly used for predictive diagnosis. The aim of the study is to draw attention to the risk of travelling to knowlesi malaria endemic areas and to raise awareness among personnel involved in the therapeutic process.

Keywords: Plasmodium knowlesi; Southeast Asia; human; malaria.

Publication types

  • Review

MeSH terms

  • Asia, Southeastern
  • Global Health
  • Humans
  • Malaria / diagnosis
  • Malaria / epidemiology*
  • Malaria / parasitology*
  • Microscopy / methods
  • Molecular Diagnostic Techniques / methods
  • Plasmodium knowlesi / isolation & purification*
  • Public Health