Incidence and Outcome of Group B Streptococcal Sepsis in Infants in Switzerland

Eric Giannoni; Christoph Berger; Martin Stocker; Philipp Agyeman; Klara M Posfay-Barbe; Ulrich Heininger; Gabriel Konetzny; Anita Niederer-Loher; Christian Kahlert; Alex Donas; Antonio Leone; Paul Hasters; Christa Relly; Walter Baer; Christoph Aebi; Luregn J Schlapbach; Swiss Pediatric Sepsis Study Group

doi:10.1097/INF.0000000000000974

Incidence and Outcome of Group B Streptococcal Sepsis in Infants in Switzerland

Pediatr Infect Dis J. 2016 Feb;35(2):222-4. doi: 10.1097/INF.0000000000000974.

Authors

Eric Giannoni¹, Christoph Berger, Martin Stocker, Philipp Agyeman, Klara M Posfay-Barbe, Ulrich Heininger, Gabriel Konetzny, Anita Niederer-Loher, Christian Kahlert, Alex Donas, Antonio Leone, Paul Hasters, Christa Relly, Walter Baer, Christoph Aebi, Luregn J Schlapbach; Swiss Pediatric Sepsis Study Group

Affiliation

¹ From the *Service of Neonatology, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland; †Infectious Diseases Service, Lausanne University Hospital, University of Lausanne, Lausanne, Switzerland; ‡Division of Infectious Diseases, Children's Research Center, University Children's Hospital Zurich, Zurich, Switzerland; §Department of Pediatrics, Children's Hospital Lucerne, Lucerne, Switzerland; ¶Department of Pediatrics, Inselspital, University of Bern, Bern, Switzerland; ‖Pediatric Infectious Diseases Unit, Children's Hospital of Geneva, University Hospitals of Geneva, Geneva, Switzerland; **Infectious Diseases and Vaccinology, University Children's Hospital Basel, Basel, Switzerland; ††Department of Pediatrics, Children's Hospital Aarau, Aarau, Switzerland; ‡‡Department of Infectious Diseases, Children's Hospital of Eastern Switzerland St. Gallen, St. Gallen, Switzerland; §§Department of Neonatology, University Hospital Zurich, Zurich, Switzerland; ¶¶Department of Pediatrics, Children's Hospital Chur, Chur, Switzerland; ‖‖Paediatric Critical Care Research Group, Mater Research Institute, University of Queensland, Brisbane, Australia; and ***Paediatric Intensive Care Unit, Lady Cilento Children's Hospital, Children's Health Queensland, Brisbane, Australia.

PMID: 26535881
DOI: 10.1097/INF.0000000000000974

Abstract

The incidence and outcome of group B streptococcal (GBS) sepsis were assessed prospectively between September 2011 and February 2015 in all tertiary care pediatric hospitals of Switzerland. We describe a low incidence of GBS early-onset sepsis (0.12/1000 livebirths) and a predominance of GBS late-onset sepsis (0.36/1000 livebirths), a pattern that has not been reported in other countries.

Publication types

Research Support, Non-U.S. Gov't

MeSH terms

Female
Hospitals, Pediatric
Humans
Incidence
Infant
Infant, Newborn
Male
Prospective Studies
Sepsis / epidemiology*
Sepsis / microbiology
Sepsis / mortality*
Streptococcal Infections / epidemiology*
Streptococcal Infections / microbiology
Streptococcal Infections / mortality*
Streptococcus agalactiae / isolation & purification*
Switzerland / epidemiology
Tertiary Care Centers
Treatment Outcome