Selective downregulation of HLA-C and HLA-E in childhood acute lymphoblastic leukaemia

Br J Haematol. 2016 Aug;174(3):477-80. doi: 10.1111/bjh.13777. Epub 2015 Nov 3.

¹ Institute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University, Düsseldorf, Germany.
² Department of Immunohaematology and Bloodtransfusion, Leiden University Medical Centre, Leiden, the Netherlands.
³ Cancer and Inflammation Program, Laboratory of Experimental Immunology, Leidos Biomedical Research Inc., Frederick National Laboratory for Cancer Research, Frederick, MD, USA.
⁴ Ragon Institute of MGH MIT and Harvard, Cambridge, MA, USA.
⁵ Department of Pediatric Oncology, Hematology and Clinical Immunology, Centre for Child and Adolescent Health, Heinrich Heine University, Düsseldorf, Germany.
⁶ Institute for Transplantation Diagnostics and Cell Therapeutics, Heinrich Heine University, Düsseldorf, Germany. markus.uhrberg@med.uni-duesseldorf.de.

No abstract available

Keywords: ALL; HLA class I; KIR; NK cells; childhood leukaemia.

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