Prevalence of Cognitive Impairment in Recently Diagnosed Type 2 Diabetes Patients: Are Chronic Inflammatory Diseases Responsible for Cognitive Decline?

PLoS One. 2015 Oct 30;10(10):e0141325. doi: 10.1371/journal.pone.0141325. eCollection 2015.

Abstract

Objective: To estimate the prevalence of cognitive impairment (CI) among patients recently diagnosed with type 2 diabetes (RDD) and to identify any relationships between CI and RDD comorbidities.

Methods: One thousand seven hundred twelve patients with RDD participated in a cross-sectional study. The patients' sociodemographic and clinical data were registered.

Results: The sample population had an average age of 51 ± 11 years, and 63.26% of the patients were female. CI was diagnosed in 38 patients (2.2%) and was more common among both females (2.8% vs. 1.3%, p = 0.063) and the elderly (0% at an age ≤ 30 years vs. 10.4% at an age > 70 years, p = 0.0001). Rheumatoid arthritis (present in 15.8% vs. absent in 2.1%) and asthma (13% vs. 2.1%) correlated significantly with CI based on the results of our logistic regression analysis.

Conclusion: Age, female gender, rheumatoid arthritis and asthma are risk factors for CI in the setting of RDD.

MeSH terms

  • Adult
  • Aged
  • Arthritis, Rheumatoid / epidemiology
  • Arthritis, Rheumatoid / psychology
  • Asthma / epidemiology
  • Asthma / psychology
  • Causality
  • Chronic Disease
  • Cognition Disorders / epidemiology*
  • Cognition Disorders / etiology
  • Cognition Disorders / immunology
  • Comorbidity
  • Cross-Sectional Studies
  • Diabetes Mellitus, Type 2 / diagnosis
  • Diabetes Mellitus, Type 2 / epidemiology
  • Diabetes Mellitus, Type 2 / psychology*
  • Disease Progression
  • Disease Susceptibility
  • Dyslipidemias / epidemiology
  • Educational Status
  • Female
  • Humans
  • Hypertension / epidemiology
  • Inflammation / epidemiology
  • Inflammation / psychology*
  • Male
  • Mexico / epidemiology
  • Middle Aged
  • Myocardial Ischemia / epidemiology
  • Neuropsychological Tests
  • Prevalence

Associated data

  • figshare/10.6084/M9.FIGSHARE.1553386

Grants and funding

The authors have no support or funding to report.