Incisional Recurrences After Endometrial Cancer Surgery

Anticancer Res. 2015 Nov;35(11):6097-104.

Abstract

Aim: The aim of the present study was to estimate the incisional recurrence (IR) rate after endometrial cancer (EC) staging surgery and analyze characteristics of affected patients.

Patients and methods: We retrospectively searched for patients with EC at 2 institutions and analyzed the occurrence of IR after open, laparoscopic, or robotic surgery. Additionally, a review of the literature was performed.

Results: Out of 2,636 patients with EC, 1,732 (65.7%), 461 (17.5%), and 443 (16.8%) had open, laparoscopic, and robotic surgery, respectively. Only 3 patients (0.11%) had IR, all after open surgery. Additionally, 38 cases of IR were identified from the literature. Patients with non-isolated IR had worse overall survival than patients with isolated IR (p=0.04). Among this latter group, combined treatments may be associated with improved survival outcome.

Conclusion: IR after EC surgery is rare and may occur after minimally-invasive or open operations. Combination of local and systemic treatments may provide favorable outcomes for patients with isolated IR.

Keywords: Endometrial cancer; incisional recurrence; laparoscopy; open surgery; port site metastases.

MeSH terms

  • Adult
  • Aged
  • Aged, 80 and over
  • Endometrial Neoplasms / mortality
  • Endometrial Neoplasms / pathology
  • Endometrial Neoplasms / surgery*
  • Female
  • Follow-Up Studies
  • Humans
  • Laparoscopy / adverse effects*
  • Middle Aged
  • Minimally Invasive Surgical Procedures / adverse effects*
  • Neoplasm Recurrence, Local / diagnosis
  • Neoplasm Recurrence, Local / etiology*
  • Neoplasm Staging
  • Postoperative Complications*
  • Prognosis
  • Retrospective Studies
  • Survival Rate