Neurobehavioral development of common marmoset monkeys

Dev Psychobiol. 2016 Mar;58(2):141-58. doi: 10.1002/dev.21360. Epub 2015 Oct 26.

Abstract

Common marmoset (Callithrix jacchus) monkeys are a resource for biomedical research and their use is predicted to increase due to the suitability of this species for transgenic approaches. Identification of abnormal neurodevelopment due to genetic modification relies upon the comparison with validated patterns of normal behavior defined by unbiased methods. As scientists unfamiliar with nonhuman primate development are interested to apply genomic editing techniques in marmosets, it would be beneficial to the field that the investigators use validated methods of postnatal evaluation that are age and species appropriate. This review aims to analyze current available data on marmoset physical and behavioral postnatal development, describe the methods used and discuss next steps to better understand and evaluate marmoset normal and abnormal postnatal neurodevelopment.

Keywords: assessment scales; behavior; common marmoset; developmental stages; neurodevelopment.

Publication types

  • Research Support, N.I.H., Extramural
  • Research Support, Non-U.S. Gov't
  • Review

MeSH terms

  • Animals
  • Behavior, Animal / physiology*
  • Callithrix / physiology*
  • Callithrix / psychology
  • Maternal Deprivation
  • Models, Animal