Magnitude, treatment, and impact of diabetes mellitus in patients hospitalized with non-ST segment elevation myocardial infarction: A community-based study

Diab Vasc Dis Res. 2016 Jan;13(1):13-20. doi: 10.1177/1479164115609027. Epub 2015 Oct 23.

Abstract

Purpose of the study: To examine differences in the characteristics, treatment practices and in-hospital outcomes of patients with and without previously diagnosed diabetes hospitalized for non-ST segment elevation myocardial infarction.

Key methods: The study cohort consisted of 3916 patients diagnosed with non-ST segment elevation myocardial infarction at all 11 central MA medical centres between 1999 and 2009, of whom 1475 (38%) had been previously diagnosed with diabetes.

Main results: Diabetic patients were more likely to have received treatment with effective cardiac medications, and to have undergone coronary bypass surgery, but were less likely to have received a percutaneous coronary intervention, than non-diabetic patients. Patients with a history of diabetes were more likely to have developed cardiogenic shock, heart failure and died during their index hospitalization than non-diabetic patients.

Main conclusion: Diabetic patients presenting with non-ST segment elevation myocardial infarction remain at high risk of developing significant clinical complications during hospitalization.

Keywords: Diabetes mellitus; NSTEMI; outcomes research; population-based study.

Publication types

  • Research Support, N.I.H., Extramural

MeSH terms

  • Aged
  • Angiotensin Receptor Antagonists / therapeutic use*
  • Angiotensin-Converting Enzyme Inhibitors / therapeutic use*
  • Calcium Channel Blockers / therapeutic use*
  • Cohort Studies
  • Comorbidity
  • Coronary Artery Bypass / statistics & numerical data*
  • Diabetes Mellitus / epidemiology*
  • Diuretics / therapeutic use*
  • Female
  • Heart Failure / epidemiology
  • Hospitalization
  • Humans
  • Hypolipidemic Agents / therapeutic use*
  • Length of Stay
  • Male
  • Myocardial Infarction / epidemiology
  • Myocardial Infarction / therapy*
  • Percutaneous Coronary Intervention / statistics & numerical data*
  • Retrospective Studies
  • Shock, Cardiogenic / epidemiology

Substances

  • Angiotensin Receptor Antagonists
  • Angiotensin-Converting Enzyme Inhibitors
  • Calcium Channel Blockers
  • Diuretics
  • Hypolipidemic Agents